SUN-337 Anti-tumorigenic Effects Of The Maternal Leucine Zipper Kinase (MELK) Inhibitor, OTSSP167, In Pre-clinical In Vivo Models Of Adrenocortical Carcinomas (ACC)

ACC is an aggressive endocrine cancer with limited therapeutic options and poor survival rates. In patients with progressive disease, standard EDP (etoposide, doxorubicin and cisplatin) chemotherapy is associated with only a modest response and progression free survival of 5 months. Mitotane, the on...

Descripción completa

Detalles Bibliográficos
Autores principales: KAR, ADWITIYA, Zhang, Yu, Yacob, Beteleham, Tompkins, Kenneth, Bagby, Stacey, Leong, Stephen, Pitts, Todd, Wierman, Margaret, Kiseljak-Vassiliades, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552789/
http://dx.doi.org/10.1210/js.2019-SUN-337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552789/
http://dx.doi.org/10.1210/js.2019-SUN-337

Ejemplares similares