Cargando…

SUN-009 N(6)-Methyladenosine Reader HNRNPA2B1 Regulates Tamoxifen-Sensitivity in Breast Cancer Cells

The RNA methylation reader Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) is a reader of the N(6)-methyladenosine (m6A) mark in mRNA and primary-miRNAs, HNRNPA2B1 interacts directly with DGCR8 in the DROSHA complex to promote processing of pri-miRNAs to precursor-miRNAs (pre-miRNAs). We r...

Descripción completa

Detalles Bibliográficos
Autores principales: Klinge, Carolyn, Rouchka, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552864/
http://dx.doi.org/10.1210/js.2019-SUN-009