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SUN-009 N(6)-Methyladenosine Reader HNRNPA2B1 Regulates Tamoxifen-Sensitivity in Breast Cancer Cells
The RNA methylation reader Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1) is a reader of the N(6)-methyladenosine (m6A) mark in mRNA and primary-miRNAs, HNRNPA2B1 interacts directly with DGCR8 in the DROSHA complex to promote processing of pri-miRNAs to precursor-miRNAs (pre-miRNAs). We r...
Autores principales: | Klinge, Carolyn, Rouchka, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552864/ http://dx.doi.org/10.1210/js.2019-SUN-009 |
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