SUN-018 Epigenetic Loss of the PIWI/piRNA Machinery in Gonadal Tumors in Androgen Insensitivity Syndrome

Abstract: There is a high frequency of Testicular Germ Cell Tumors (TGCT) in 46,XY individuals with disorders of sexual development (46,XY DSD), which include Androgen Insensitivity Syndrome (AIS). That TGCT risk leads to pragmatic gonadectomy in these patients with several further implications. A b...

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Detalles Bibliográficos
Autores principales: Batista, Rafael, Nishi, Mirian, Rodrigues, Andresa, Costa, Elaine Maria, Domenice, Sorahia, Mendonca, Berenice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553020/
http://dx.doi.org/10.1210/js.2019-SUN-018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553020/
http://dx.doi.org/10.1210/js.2019-SUN-018

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