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SUN-018 Epigenetic Loss of the PIWI/piRNA Machinery in Gonadal Tumors in Androgen Insensitivity Syndrome
Abstract: There is a high frequency of Testicular Germ Cell Tumors (TGCT) in 46,XY individuals with disorders of sexual development (46,XY DSD), which include Androgen Insensitivity Syndrome (AIS). That TGCT risk leads to pragmatic gonadectomy in these patients with several further implications. A b...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553020/ http://dx.doi.org/10.1210/js.2019-SUN-018 |