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SUN-016 27-Hydroxycholesterol a Selective Estrogen Receptor Modulator: Profiling 27-Hydroxycholesterol Effects on Estrogen Receptor Activity in Mice
27-Hydroxycholesterol (27-HC) is the most prevalent metabolite of cholesterol in circulation, and also the first identified endogenous selective estrogen receptor (ER) modulator (SERM) (1). Previously, we found that 27-HC acts as an agonist of ER in breast cancer cells, while it acts as an antagonis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553081/ http://dx.doi.org/10.1210/js.2019-SUN-016 |