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SUN-454 Rationale and Methods for a Phase II Trial Evaluating Osilodrostat in Pediatric Patients with Cushing's Disease

Background: Cushing’s disease (CD) is a rare disease associated with significant morbidity and mortality, with 2-5 new cases per million per year, of which 10% occur in children (Stratakis CA. Endocrinol Metab Clin North Am 2012;41:793-803). In children, CD presents with a combination of weight gain...

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Detalles Bibliográficos
Autores principales: Savage, Martin, Shah, Nalini, Wojna, Judi, Han, Kevin, Roughton, Michael, Combes, François Pierre, Pultar, Philippe, Storr, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553121/
http://dx.doi.org/10.1210/js.2019-SUN-454