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SUN-022 Absence of Neuronal Androgen Receptor (AR) Improves Glucose Homeostasis in Female Mice

Androgen excess predisposes females to type 2 diabetes (1). Using mouse models of testosterone excess, we reported that this is due, at least partially, to excess AR activation in pancreatic β-cells and neurons. Excess AR activation in β-cells causes β-cell dysfunction while excess AR activation in...

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Detalles Bibliográficos
Autores principales: Morford, Jamie, Mauvais-Jarvis, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553285/
http://dx.doi.org/10.1210/js.2019-SUN-022