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SUN-453 Absence of Crooke's Hyaline Changes May Predict Worse Outcomes in Patients with Cushing Disease

Background: Autonomous glucocorticoid excess in patients with Cushing disease (CD) may lead to negative feedback suppression, resulting in Crooke's hyaline change (CC) of the non-tumorous corticotrophs in the pituitary. Objective: To determine the prognostic implication of evidence of CC on his...

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Detalles Bibliográficos
Autores principales: Akirov, Amit, Asa, Sylvia, Larouche, Vincent, Mete, Ozgur, Ezzat, Shereen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553297/
http://dx.doi.org/10.1210/js.2019-SUN-453