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SUN-109 PTEN Regulates Differentiation and Proliferation of Aging Preadipocytes
Background: The tumor suppressor gene phosphatase and tensin homologe (PTEN) is one of the most frequently altered genes in human cancer. It antagonizes the PI3K/AKT/mTOR pathway, which is activated by various factors like IGF-1 or insulin and promotes cell growth and proliferation. Germline PTEN mu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553313/ http://dx.doi.org/10.1210/js.2019-SUN-109 |