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SUN-466 Gestational Diabetes Alters Hypothalamic Development, Microglial Activation, and Insulin Signaling in Offspring

Gestational diabetes mellitus (GDM) is characterized by maternal insulin resistance during pregnancy, leading to high blood glucose levels. Offspring of a GDM pregnancy often have high birth weight that continues through life. GDM influence on developing hypothalamic tanycytes may underlie this outc...

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Detalles Bibliográficos
Autores principales: Gonzalez, Rachel, Weis, Karen, Raetzman, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553328/
http://dx.doi.org/10.1210/js.2019-SUN-466