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SUN-096 Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol and Withaferin A
Leptin is an adipocyte-derived hormone involved in the regulation of food intake and energy expenditure. Since obese subjects generally have leptin resistance, leptin sensitizers are expected as anti-obesity drugs. It has been reported that endoplasmic reticulum (ER) stress in the hypothalamus plays...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553405/ http://dx.doi.org/10.1210/js.2019-SUN-096 |