Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P(2) That Regulates Neuronal Excitability

There is increasing evidence that the lysosome is involved in the pathogenesis of a variety of neurodegenerative disorders. Thus, mechanisms that link lysosome dysfunction to the disruption of neuronal homeostasis offer opportunities to understand the molecular underpinnings of neurodegeneration and...

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Detalles Bibliográficos
Autores principales: Vivas, Oscar, Tiscione, Scott A., Dixon, Rose E., Ory, Daniel S., Dickson, Eamonn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553496/
https://www.ncbi.nlm.nih.gov/pubmed/31141688
http://dx.doi.org/10.1016/j.celrep.2019.04.099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553496/
https://www.ncbi.nlm.nih.gov/pubmed/31141688
http://dx.doi.org/10.1016/j.celrep.2019.04.099

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