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Adventitious Virus Detection in Cells by High-Throughput Sequencing of Newly Synthesized RNAs: Unambiguous Differentiation of Cell Infection from Carryover of Viral Nucleic Acids

The use of high-throughput sequencing (HTS) to identify viruses in biologicals differs from current molecular approaches, since its use enables an unbiased approach to detection without the need to design specific primers to preamplify target sequences. Its broad range of detection and analytical se...

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Detalles Bibliográficos
Autores principales: Cheval, Justine, Muth, Erika, Gonzalez, Gaëlle, Coulpier, Muriel, Beurdeley, Pascale, Cruveiller, Stéphane, Eloit, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553555/
https://www.ncbi.nlm.nih.gov/pubmed/31167947
http://dx.doi.org/10.1128/mSphere.00298-19