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CRL4(Mahj) E3 ubiquitin ligase promotes neural stem cell reactivation

The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown. Here, we show that CRL4(Mahj), an evolutionarily c...

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Detalles Bibliográficos
Autores principales: Ly, Phuong Thao, Tan, Ye Sing, Koe, Chwee Tat, Zhang, Yingjie, Xie, Gengqiang, Endow, Sharyn, Deng, Wu-Min, Yu, Fengwei, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553684/
https://www.ncbi.nlm.nih.gov/pubmed/31170139
http://dx.doi.org/10.1371/journal.pbio.3000276