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CRL4(Mahj) E3 ubiquitin ligase promotes neural stem cell reactivation
The ability of neural stem cells (NSCs) to transit between quiescence and proliferation is crucial for brain development and homeostasis. Drosophila Hippo pathway maintains NSC quiescence, but its regulation during brain development remains unknown. Here, we show that CRL4(Mahj), an evolutionarily c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553684/ https://www.ncbi.nlm.nih.gov/pubmed/31170139 http://dx.doi.org/10.1371/journal.pbio.3000276 |