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Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat

The Hirschsprung disease (HSCR) is an inherited disease that is controlled by multiple genes and has a complicated genetic mechanism. HSCR patients suffer from various extents of constipation due to dysplasia of the enteric nervous system (ENS), which can be so severe as to cause complete intestinal...

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Detalles Bibliográficos
Autores principales: Wang, Jinxi, Dang, Ruihua, Miyasaka, Yoshiki, Hattori, Kousuke, Torigoe, Daisuke, Okamura, Tadashi, Tag-EI-Din-Hassan, Hassan T., Morimatsu, Masami, Mashimo, Tomoji, Agui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553694/
https://www.ncbi.nlm.nih.gov/pubmed/31170185
http://dx.doi.org/10.1371/journal.pone.0217132