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An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion

Toxoplasma gondii is an apicomplexan parasite with the ability to use foodborne, zoonotic, and congenital routes of transmission that causes severe disease in immunocompromised patients. The parasites harbor a lysosome-like organelle, termed the "Vacuolar Compartment/Plant-Like Vacuole" (V...

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Detalles Bibliográficos
Autores principales: Thornton, L. Brock, Teehan, Paige, Floyd, Katherine, Cochrane, Christian, Bergmann, Amy, Riegel, Bryce, Stasic, Andrew J., Di Cristina, Manlio, Moreno, Silvia N. J., Roepe, Paul D., Dou, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553793/
https://www.ncbi.nlm.nih.gov/pubmed/31170269
http://dx.doi.org/10.1371/journal.ppat.1007775