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Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle

The function of AarF domain-containing kinase 1 (ADCK1) has not been thoroughly revealed. Here we identified that ADCK1 utilizes YME1-like 1 ATPase (YME1L1) to control optic atrophy 1 (OPA1) and inner membrane mitochondrial protein (IMMT) in regulating mitochondrial dynamics and cristae structure. W...

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Detalles Bibliográficos
Autores principales: Yoon, Woongchang, Hwang, Sun-Hong, Lee, Sang-Hee, Chung, Jongkyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553794/
https://www.ncbi.nlm.nih.gov/pubmed/31125351
http://dx.doi.org/10.1371/journal.pgen.1008184