Divergent Allele Advantage Provides a Quantitative Model for Maintaining Alleles with a Wide Range of Intrinsic Merits

The Major Histocompatibility Complex (MHC) is the most genetically diverse region of the genome in most vertebrates. Some form of balancing selection is necessary to account for the extreme diversity, but the precise mechanism of balancing selection is unknown. Due to the way MHC molecules determine...

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Detalles Bibliográficos
Autores principales: Stefan, Thorsten, Matthews, Louise, Prada, Joaquin M., Mair, Colette, Reeve, Richard, Stear, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553829/
https://www.ncbi.nlm.nih.gov/pubmed/30952668
http://dx.doi.org/10.1534/genetics.119.302022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553829/
https://www.ncbi.nlm.nih.gov/pubmed/30952668
http://dx.doi.org/10.1534/genetics.119.302022

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