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DNA Rereplication Is Susceptible to Nucleotide-Level Mutagenesis

The sources of genome instability, a hallmark of cancer, remain incompletely understood. One potential source is DNA rereplication, which arises when the mechanisms that prevent the reinitiation of replication origins within a single cell cycle are compromised. Using the budding yeast Saccharomyces...

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Detalles Bibliográficos
Autores principales: Bui, Duyen T., Li, Joachim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553831/
https://www.ncbi.nlm.nih.gov/pubmed/31028114
http://dx.doi.org/10.1534/genetics.119.302194