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DNA Rereplication Is Susceptible to Nucleotide-Level Mutagenesis
The sources of genome instability, a hallmark of cancer, remain incompletely understood. One potential source is DNA rereplication, which arises when the mechanisms that prevent the reinitiation of replication origins within a single cell cycle are compromised. Using the budding yeast Saccharomyces...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553831/ https://www.ncbi.nlm.nih.gov/pubmed/31028114 http://dx.doi.org/10.1534/genetics.119.302194 |