Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance

Recent studies have affirmed that higher-order epistasis is ubiquitous and can have large effects on complex traits. Yet, we lack frameworks for understanding how epistatic interactions are influenced by central features of cell physiology. In this study, we assess how protein quality control machin...

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Detalles Bibliográficos
Autores principales: Guerrero, Rafael F., Scarpino, Samuel V., Rodrigues, João V., Hartl, Daniel L., Ogbunugafor, C. Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553834/
https://www.ncbi.nlm.nih.gov/pubmed/31015194
http://dx.doi.org/10.1534/genetics.119.302138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553834/
https://www.ncbi.nlm.nih.gov/pubmed/31015194
http://dx.doi.org/10.1534/genetics.119.302138

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