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Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance
Recent studies have affirmed that higher-order epistasis is ubiquitous and can have large effects on complex traits. Yet, we lack frameworks for understanding how epistatic interactions are influenced by central features of cell physiology. In this study, we assess how protein quality control machin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553834/ https://www.ncbi.nlm.nih.gov/pubmed/31015194 http://dx.doi.org/10.1534/genetics.119.302138 |