ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma

Purpose: Ornithine decarboxylase 1 (ODC1)–an oncogene involved in the biosynthesis of polyamines–is commonly upregulated and associated with poor prognosis in numerous cancers. However, the role and mechanism of ODC1 in hepatocellular carcinoma (HCC) remains unclear. The aim of the present study was...

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Detalles Bibliográficos
Autores principales: Ye, Zi, Zeng, Zhirui, Shen, Yiyi, Yang, Qiang, Chen, Duidui, Chen, Zubing, Shen, Shiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553997/
https://www.ncbi.nlm.nih.gov/pubmed/31239700
http://dx.doi.org/10.2147/OTT.S198341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553997/
https://www.ncbi.nlm.nih.gov/pubmed/31239700
http://dx.doi.org/10.2147/OTT.S198341

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