Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform

In the field of quantitative proteomics, the Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) technology has demonstrated efficacy for proteome monitoring despite its lack of a consensus for data handling. In the present study, after peptide and protein identification, we compared the wi...

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Detalles Bibliográficos
Autores principales: Burat, Bastien, Gonzalez, Julien, Sauvage, François-Ludovic, Aouad, Hassan, Arnion, Hélène, Pinault, Emilie, Marquet, Pierre, Essig, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554230/
https://www.ncbi.nlm.nih.gov/pubmed/31110078
http://dx.doi.org/10.1042/BSR20190904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554230/
https://www.ncbi.nlm.nih.gov/pubmed/31110078
http://dx.doi.org/10.1042/BSR20190904

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