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Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform
In the field of quantitative proteomics, the Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) technology has demonstrated efficacy for proteome monitoring despite its lack of a consensus for data handling. In the present study, after peptide and protein identification, we compared the wi...
Autores principales: | Burat, Bastien, Gonzalez, Julien, Sauvage, François-Ludovic, Aouad, Hassan, Arnion, Hélène, Pinault, Emilie, Marquet, Pierre, Essig, Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554230/ https://www.ncbi.nlm.nih.gov/pubmed/31110078 http://dx.doi.org/10.1042/BSR20190904 |
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