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Significance of IL-6 Deficiency in Recognition Memory in Young Adult and Aged Mice

Chronic peripheral elevation of interleukin 6 (IL-6) in humans is associated with cognitive deficits. 4- and 24-month-old IL-6-deficient C57BL/6J (IL-6KO) and reference wild-type (WT) mice were tested in an object recognition test. Discrimination ratios and recognition indexes were significantly low...

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Detalles Bibliográficos
Autores principales: Bialuk, Izabela, Jakubów, Piotr, Winnicka, Maria Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554246/
https://www.ncbi.nlm.nih.gov/pubmed/31129771
http://dx.doi.org/10.1007/s10519-019-09959-6