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Significance of IL-6 Deficiency in Recognition Memory in Young Adult and Aged Mice
Chronic peripheral elevation of interleukin 6 (IL-6) in humans is associated with cognitive deficits. 4- and 24-month-old IL-6-deficient C57BL/6J (IL-6KO) and reference wild-type (WT) mice were tested in an object recognition test. Discrimination ratios and recognition indexes were significantly low...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554246/ https://www.ncbi.nlm.nih.gov/pubmed/31129771 http://dx.doi.org/10.1007/s10519-019-09959-6 |