Genetics, Mechanisms, and Therapeutic Progress in Polyglutamine Spinocerebellar Ataxias

Autosomal dominant cerebellar ataxias (ADCAs) are a group of neurodegenerative disorders characterized by degeneration of the cerebellum and its connections. All ADCAs have progressive ataxia as their main clinical feature, frequently accompanied by dysarthria and oculomotor deficits. The most commo...

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Detalles Bibliográficos
Autores principales: Buijsen, Ronald A.M., Toonen, Lodewijk J.A., Gardiner, Sarah L., van Roon-Mom, Willeke M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554265/
https://www.ncbi.nlm.nih.gov/pubmed/30607747
http://dx.doi.org/10.1007/s13311-018-00696-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554265/
https://www.ncbi.nlm.nih.gov/pubmed/30607747
http://dx.doi.org/10.1007/s13311-018-00696-y

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