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Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice

Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabo...

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Detalles Bibliográficos
Autores principales: Pharaoh, Gavin, Sataranatarajan, Kavithalakshmi, Street, Kaitlyn, Hill, Shauna, Gregston, Jake, Ahn, Bumsoo, Kinter, Caroline, Kinter, Michael, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554287/
https://www.ncbi.nlm.nih.gov/pubmed/31213966
http://dx.doi.org/10.3389/fnins.2019.00487