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Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice
Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabo...
Autores principales: | Pharaoh, Gavin, Sataranatarajan, Kavithalakshmi, Street, Kaitlyn, Hill, Shauna, Gregston, Jake, Ahn, Bumsoo, Kinter, Caroline, Kinter, Michael, Van Remmen, Holly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554287/ https://www.ncbi.nlm.nih.gov/pubmed/31213966 http://dx.doi.org/10.3389/fnins.2019.00487 |
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