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Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice
The tauopathy-like phenotype observed in the rTg4510 mouse line, in which human tau(P301L) expression specifically within the forebrain can be temporally controlled, has largely been attributed to high overexpression of mutant human tau in the forebrain region. Unexpectedly, we found that in a diffe...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554306/ https://www.ncbi.nlm.nih.gov/pubmed/31171783 http://dx.doi.org/10.1038/s41467-019-10428-1 |