C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases

C3 glomerulopathy (C3G) is a severe kidney disease, which is caused by defective regulation of the alternative complement pathway. Disease pathogenesis is heterogeneous and is caused by both autoimmune and genetic factors. Here we characterized IgG autoantibodies derived from 33 patients with autoim...

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Detalles Bibliográficos
Autores principales: Zhao, Fei, Afonso, Sara, Lindner, Susanne, Hartmann, Andrea, Löschmann, Ina, Nilsson, Bo, Ekdahl, Kristina N., Weber, Lutz T., Habbig, Sandra, Schalk, Gesa, Kirschfink, Michael, Zipfel, Peter F., Skerka, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554336/
https://www.ncbi.nlm.nih.gov/pubmed/31214159
http://dx.doi.org/10.3389/fimmu.2019.01030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554336/
https://www.ncbi.nlm.nih.gov/pubmed/31214159
http://dx.doi.org/10.3389/fimmu.2019.01030

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