Alcohol exposure alters pre-mRNA splicing of antiapoptotic Mcl-1L isoform and induces apoptosis in neural progenitors and immature neurons

Alternative splicing and expression of splice variants of genes in the brain may lead to the modulation of protein functions, which may ultimately influence behaviors associated with alcohol dependence and neurotoxicity. We recently showed that ethanol exposure can lead to pre-mRNA missplicing of Mc...

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Detalles Bibliográficos
Autores principales: Donadoni, Martina, Cicalese, Stephanie, Sarkar, Dipak K., Chang, Sulie L., Sariyer, Ilker Kudret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554352/
https://www.ncbi.nlm.nih.gov/pubmed/31171771
http://dx.doi.org/10.1038/s41419-019-1673-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554352/
https://www.ncbi.nlm.nih.gov/pubmed/31171771
http://dx.doi.org/10.1038/s41419-019-1673-3

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