Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons

Subcellular RNAseq promises to dissect transcriptional dynamics but is not well characterized. Furthermore, FACS may introduce bias but has not been benchmarked genome-wide. Finally, D1 and D2 dopamine receptor-expressing medium spiny neurons (MSNs) of the nucleus accumbens (NAc) are fundamental to...

Descripción completa

Detalles Bibliográficos
Autores principales: Kronman, Hope, Richter, Felix, Labonté, Benoit, Chandra, Ramesh, Zhao, Shan, Hoffman, Gabriel, Lobo, Mary Kay, Schadt, Eric E., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554355/
https://www.ncbi.nlm.nih.gov/pubmed/31171808
http://dx.doi.org/10.1038/s41598-019-44798-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554355/
https://www.ncbi.nlm.nih.gov/pubmed/31171808
http://dx.doi.org/10.1038/s41598-019-44798-9

Ejemplares similares