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Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma

Aberrant microRNA-708 (miR-708) expression is frequently reported in cancer studies; however, its role in glioma has not been examined in detail. We investigated miR-708 function in glioma and revealed that miR-708 expression was significantly down-regulated in glioma tissues and cell lines. Restora...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Deng, Xubin, Chen, Weiquan, Shi, Pengwei, Lian, Mei, Wang, Hongxiao, Wang, Kewan, Qian, Dadi, Xiao, Dong, Long, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554356/
https://www.ncbi.nlm.nih.gov/pubmed/31171769
http://dx.doi.org/10.1038/s41419-019-1671-5