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Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

There is a strong need for procedures that enable context and application dependent validation of antibodies. Here, we applied a magnetic bead assisted workflow and immunoprecipitation mass spectrometry (IP-MS/MS) to assess antibody selectivity for the detection of proteins in human plasma. A resour...

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Detalles Bibliográficos
Autores principales: Fredolini, Claudia, Byström, Sanna, Sanchez-Rivera, Laura, Ioannou, Marina, Tamburro, Davide, Pontén, Fredrik, Branca, Rui M., Nilsson, Peter, Lehtiö, Janne, Schwenk, Jochen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554399/
https://www.ncbi.nlm.nih.gov/pubmed/31171813
http://dx.doi.org/10.1038/s41598-019-43552-5