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The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis

Non-obstructive azoospermia (NOA) severely affects male infertility, however, the deep mechanisms of this disease are rarely interpreted. In this study, we find that undifferentiated spermatogonial stem cells (SSCs) still exist in the basal compartment of the seminiferous tubules and the blood–testi...

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Detalles Bibliográficos
Autores principales: Zhu, Ruilou, Wang, Jiangnan, Feng, Tianxiang, Hu, Xuechun, Jiang, Chen, Wang, Xiuxing, Li, Kang, Sang, Yongjuan, Hua, Yue, Sun, Haixiang, Yao, Bing, Li, Chaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554403/
https://www.ncbi.nlm.nih.gov/pubmed/31171774
http://dx.doi.org/10.1038/s41419-019-1688-9