T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection

The enzyme acid sphingomyelinase (ASM) hydrolyzes sphingomyelin to ceramide and is thereby involved in several cellular processes such as differentiation, proliferation, and apoptosis in different cell types. However, the function of ASM in T cells is still not well characterized. Here, we used T ce...

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Detalles Bibliográficos
Autores principales: Hose, Matthias, Günther, Anne, Abberger, Hanna, Begum, Salina, Korencak, Marek, Becker, Katrin A., Buer, Jan, Westendorf, Astrid M., Hansen, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554418/
https://www.ncbi.nlm.nih.gov/pubmed/31214184
http://dx.doi.org/10.3389/fimmu.2019.01225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554418/
https://www.ncbi.nlm.nih.gov/pubmed/31214184
http://dx.doi.org/10.3389/fimmu.2019.01225

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