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Long-Chain Fatty Acid Receptors Mediate Relaxation of the Porcine Lower Esophageal Sphincter

Long-chain fatty acids activate the free fatty acid receptor 1 (FFA1) and FFA4. In the gastrointestinal system, FFA1 and FFA4 have been found in the pancreas and intestine. Fatty food and decreased lower esophageal sphincter (LES) motility are associated with gastroesophageal reflux disease. The eff...

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Detalles Bibliográficos
Autores principales: Tsai, Ching-Chung, Li, Yi-Chen, Chang, Li-Ching, Tey, Shu-Leei, Lin, Kai-Jen, Huang, Shih-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554435/
https://www.ncbi.nlm.nih.gov/pubmed/31214048
http://dx.doi.org/10.3389/fphys.2019.00676