Tempol Protects Against Acetaminophen Induced Acute Hepatotoxicity by Inhibiting Oxidative Stress and Apoptosis

Acetaminophen (APAP)-induced acute hepatotoxicity is the leading cause of drug-induced acute liver failure. The aim of this study was to evaluate the effects of 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (tempol) on the protection of APAP-induced hepatotoxicity in mice. Mice were pretreated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Zheng, Wang, Chenyu, Zhang, Junjie, Li, Xiwang, Hu, Junhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554449/
https://www.ncbi.nlm.nih.gov/pubmed/31214044
http://dx.doi.org/10.3389/fphys.2019.00660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554449/
https://www.ncbi.nlm.nih.gov/pubmed/31214044
http://dx.doi.org/10.3389/fphys.2019.00660

Ejemplares similares