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Tempol Protects Against Acetaminophen Induced Acute Hepatotoxicity by Inhibiting Oxidative Stress and Apoptosis

Acetaminophen (APAP)-induced acute hepatotoxicity is the leading cause of drug-induced acute liver failure. The aim of this study was to evaluate the effects of 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (tempol) on the protection of APAP-induced hepatotoxicity in mice. Mice were pretreated with...

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Detalles Bibliográficos
Autores principales:	Ge, Zheng, Wang, Chenyu, Zhang, Junjie, Li, Xiwang, Hu, Junhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554449/ https://www.ncbi.nlm.nih.gov/pubmed/31214044 http://dx.doi.org/10.3389/fphys.2019.00660

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