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GDP-Mannose Pyrophosphorylase: A Biologically Validated Target for Drug Development Against Leishmaniasis

Leishmaniases are neglected tropical diseases that threaten about 350 million people in 98 countries around the world. In order to find new antileishmanial drugs, an original approach consists in reducing the pathogenic effect of the parasite by impairing the glycoconjugate biosynthesis, necessary f...

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Detalles Bibliográficos
Autores principales: Pomel, Sébastien, Mao, Wei, Ha-Duong, Tâp, Cavé, Christian, Loiseau, Philippe M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554559/
https://www.ncbi.nlm.nih.gov/pubmed/31214516
http://dx.doi.org/10.3389/fcimb.2019.00186