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Genome-Wide Association Study of Tacrolimus Pharmacokinetics Identifies Novel Single Nucleotide Polymorphisms in the Convalescence and Stabilization Periods of Post-transplant Liver Function

After liver transplantation, the liver function of a patient is gradually restored over a period of time that can be divided into a convalescence period (CP) and a stabilizing period (SP). The plasma concentration of tacrolimus, an immunosuppressant commonly used to prevent organ rejection, varies a...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Zhang, Chengdong, Li, Lei, Ou, Baochi, Yuan, Liyun, Zhang, Tao, Fan, Junwei, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554639/
https://www.ncbi.nlm.nih.gov/pubmed/31214251
http://dx.doi.org/10.3389/fgene.2019.00528