Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications

Unexpected cardiac adverse effects are the leading causes of discontinuation of clinical trials and withdrawal of drugs from the market. Since the original observations in the mid-90s, it has been well established that cardiovascular risk factors and comorbidities (such as ageing, hyperlipidaemia, a...

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Detalles Bibliográficos
Autores principales: Ferdinandy, Péter, Baczkó, István, Bencsik, Péter, Giricz, Zoltán, Görbe, Anikó, Pacher, Pál, Varga, Zoltán V, Varró, András, Schulz, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Clinical Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554653/
https://www.ncbi.nlm.nih.gov/pubmed/29982507
http://dx.doi.org/10.1093/eurheartj/ehy365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554653/
https://www.ncbi.nlm.nih.gov/pubmed/29982507
http://dx.doi.org/10.1093/eurheartj/ehy365

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