Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection

BACKGROUND & AIMS: Epithelial cells are joined by tight junctions (TJs) to form a cell sheet. In the stomach, epithelial cell sheet forms an essential barrier against gastric material, including gastric acid. Although the decreased expression of stomach-type claudin-18 (stCldn18), a TJ protein,...

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Detalles Bibliográficos
Autores principales: Suzuki, Koya, Sentani, Kazuhiro, Tanaka, Hiroo, Yano, Tomoki, Suzuki, Kazuo, Oshima, Masanobu, Yasui, Wataru, Tamura, Atsushi, Tsukita, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554658/
https://www.ncbi.nlm.nih.gov/pubmed/30910700
http://dx.doi.org/10.1016/j.jcmgh.2019.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554658/
https://www.ncbi.nlm.nih.gov/pubmed/30910700
http://dx.doi.org/10.1016/j.jcmgh.2019.03.003

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