Nf1 loss promotes Kras‐driven lung adenocarcinoma and results in Psat1‐mediated glutamate dependence

Mutations to KRAS are recurrent in lung adenocarcinomas (LUAD) and are daunting to treat due to the difficulties in KRAS oncoprotein inhibition. A possible resolution to this problem may lie with co‐mutations to other genes that also occur in KRAS‐driven LUAD that may provide alternative therapeutic...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojing, Min, Shengping, Liu, Hongli, Wu, Nan, Liu, Xincheng, Wang, Tao, Li, Wei, Shen, Yuanbing, Wang, Hongtao, Qian, Zhongqing, Xu, Huanbai, Zhao, Chengling, Chen, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554671/
https://www.ncbi.nlm.nih.gov/pubmed/31036704
http://dx.doi.org/10.15252/emmm.201809856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554671/
https://www.ncbi.nlm.nih.gov/pubmed/31036704
http://dx.doi.org/10.15252/emmm.201809856

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