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Nf1 loss promotes Kras‐driven lung adenocarcinoma and results in Psat1‐mediated glutamate dependence
Mutations to KRAS are recurrent in lung adenocarcinomas (LUAD) and are daunting to treat due to the difficulties in KRAS oncoprotein inhibition. A possible resolution to this problem may lie with co‐mutations to other genes that also occur in KRAS‐driven LUAD that may provide alternative therapeutic...
Autores principales: | Wang, Xiaojing, Min, Shengping, Liu, Hongli, Wu, Nan, Liu, Xincheng, Wang, Tao, Li, Wei, Shen, Yuanbing, Wang, Hongtao, Qian, Zhongqing, Xu, Huanbai, Zhao, Chengling, Chen, Yuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554671/ https://www.ncbi.nlm.nih.gov/pubmed/31036704 http://dx.doi.org/10.15252/emmm.201809856 |
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