OR18-4 Beneficial Effect on Sperm Production of Leflutrozole in Men with Obesity-Associated Secondary Hypogonadotropic Hypogonadism: Results from a Phase II Study

Introduction: Excess aromatase activity in adipose tissue has been linked to increased conversion of testosterone (T) to estradiol, resulting in high estradiol levels and suppressing gonadotropins. In obese men, this can cause obesity-associated hypogonadotropic hypogonadism (OHH) with decreased fer...

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Detalles Bibliográficos
Autores principales: Jones, Thomas, Dobs, Adrian, MacKinnon, Alastair, Parkin, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Reproductive Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554756/
http://dx.doi.org/10.1210/js.2019-OR18-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554756/
http://dx.doi.org/10.1210/js.2019-OR18-4

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