OR23-5 A Model “Obesogen”, Tributyltin, Promotes Steatosis in Human Liver Cells by Upregulating Lipogenic Gene Expression as a Consequence of Alterations in Both Genomic and Non-Genomic Signaling

Non-alcoholic fatty liver disease (NAFLD) is a worldwide problem. In addition to known risk factors, such as consumption of high-fat diets, animal data suggests a clear causal link between exposure to obesogenic chemicals, such as tributyltin (TBT), and NAFLD development. TBT can directly bind and p...

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Detalles Bibliográficos
Autores principales: Chen, Yue, Trevino, Lindsey, Katz, Tiffany, Hamilton, Ross, Malovannaya, Anna, Stossi, Fabio, Coarfa, Cristian, Foulds, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Endocrine Disruption
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554758/
http://dx.doi.org/10.1210/js.2019-OR23-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554758/
http://dx.doi.org/10.1210/js.2019-OR23-5

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