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OR23-5 A Model “Obesogen”, Tributyltin, Promotes Steatosis in Human Liver Cells by Upregulating Lipogenic Gene Expression as a Consequence of Alterations in Both Genomic and Non-Genomic Signaling
Non-alcoholic fatty liver disease (NAFLD) is a worldwide problem. In addition to known risk factors, such as consumption of high-fat diets, animal data suggests a clear causal link between exposure to obesogenic chemicals, such as tributyltin (TBT), and NAFLD development. TBT can directly bind and p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554758/ http://dx.doi.org/10.1210/js.2019-OR23-5 |