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OR17-1 Changes in the Hypothalamic-Pituitary-Adrenal Axis during Pediatric Critical Illness

Critical illness in adults is hallmarked by prolonged hypercortisolism and a rapid decrease in ACTH. The high cortisol is explained by reduced cortisol breakdown and a decrease in cortisol binding proteins, rather than by adrenal production. In critically ill children, the evolution of the changes i...

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Detalles Bibliográficos
Autores principales: Jacobs, An, Vanhorebeek, Ilse, Derese, Inge, Vander Perre, Sarah, Wouters, Pieter, Verbruggen, Sascha, Joosten, Koen, Van den Berghe, Greet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554779/
http://dx.doi.org/10.1210/js.2019-OR17-1